The c-Jun N-terminal Kinase (JNK)-binding Protein (JNKBP1) Acts as a Negative Regulator of NOD2 Protein Signaling by Inhibiting Its Oligomerization Process

NOD2 is one of the best characterized members of the cytosolic NOD-like receptor family. NOD2 is able to sense muramyl dipeptide, a specific bacterial cell wall component, and to subsequently induce various signaling pathways leading to NF-κB activation and autophagy, both events contributing to an...

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Main Authors: Lecat, Aurore, Di Valentin, Emmanuel, Somja, Joan, Jourdan, Samuel, Fillet, Marianne, Kufer, Thomas A., Habraken, Yvette, Sadzot, Catherine, Louis, Edouard, Delvenne, Philippe, Piette, Jacques, Legrand-Poels, Sylvie
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436148/
https://ncbi.nlm.nih.gov/pubmed/22700971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.355545
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