Engagement of Nucleotide-binding Oligomerization Domain-containing Protein 1 (NOD1) by Receptor-interacting Protein 2 (RIP2) Is Insufficient for Signal Transduction

Following activation, the cytoplasmic pattern recognition receptor nucleotide-binding oligomerization domain-containing protein 1 (NOD1) interacts with its adaptor protein receptor-interacting protein 2 (RIP2) to propagate immune signaling and initiate a proinflammatory immune response. This interac...

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Autores principales: Mayle, Sophie, Boyle, Joseph P., Sekine, Eiki, Zurek, Birte, Kufer, Thomas A., Monie, Tom P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132792/
https://ncbi.nlm.nih.gov/pubmed/24958724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557900
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