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Signaling pathways in aged T cells – a reflection of T cell differentiation, cell senescence and host environment

With increasing age, the ability of the immune system to protect against new antigenic challenges or to control chronic infections erodes. Decline in thymic function and cumulating antigenic experiences of acute and chronic infections threaten T cell homeostasis, but insufficiently explain the faili...

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Bibliografski detalji
Glavni autori: Goronzy, Jörg J., Li, Guangjin, Yu, Mingcan, Weyand, Cornelia M.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435478/
https://ncbi.nlm.nih.gov/pubmed/22560928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2012.04.003
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