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Epigenetic regulation of killer immunoglobulin–like receptor expression in T cells
With increasing age, T cells gain expression of killer immunoglobulin–like receptors (KIRs) that transmit negative signals and dampen the immune response. KIR expression is induced in CD4 and CD8 T cells by CpG DNA demethylation suggesting epigenetic control. To define the mechanisms that underlie t...
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| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society of Hematology
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765678/ https://ncbi.nlm.nih.gov/pubmed/19628706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-200170 |
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