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Epigenetic mechanisms of age-dependent KIR2DL4 expression in T cells

Killer Ig-like receptor (KIR) expression is mostly restricted to NK cells controlling their activation. With increasing age, KIRs are expressed on T cells and contribute to age-related diseases. We examined epigenetic mechanisms that determine the competency of T cells to transcribe KIR2DL4. Compare...

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Detalhes bibliográficos
Main Authors: Li, Guangjin, Weyand, Cornelia M., Goronzy, Jörg J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516893/
https://ncbi.nlm.nih.gov/pubmed/18586981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0807583
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