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Promoter choice and translational repression determine cell type–specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages

CD85j (ILT2/LILRB1/LIR-1) is an inhibitory receptor that recognizes major histocompatibility complex (MHC) class Ia and Ib alleles that are widely expressed on all cell types. On ligand recognition, CD85j diminishes kinase activity by recruiting phosphatases to motifs within its cytoplasmic domain....

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Bibliografiska uppgifter
Huvudupphovsmän: Lamar, David L., Weyand, Cornelia M., Goronzy, Jörg J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858479/
https://ncbi.nlm.nih.gov/pubmed/20194892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-243493
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