HCV Infection Induces a Unique Hepatic Innate Immune Response Associated With Robust Production of Type III Interferons

BACKGROUND & AIMS: Polymorphisms in the IL28B gene have been associated with clearance of hepatitis C virus (HCV), indicating a role for type III interferons (IFNs) in HCV infection. Little is known about the function of type III IFNs in intrinsic antiviral innate immunity. METHODS: We used in v...

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Huvudupphovsmän: THOMAS, EMMANUEL, GONZALEZ, VERONICA D., LI, QISHENG, MODI, ANKIT A., CHEN, WEIPING, NOUREDDIN, MAZEN, ROTMAN, YARON, LIANG, T. JAKE
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435150/
https://ncbi.nlm.nih.gov/pubmed/22248663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.12.055
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