S-adenosyl methionine improves early viral responses and interferon-stimulated gene induction in hepatitis C nonresponders

BACKGROUND & AIMS: Fewer than half of patients infected with Hepatitis C virus (HCV) achieve sustained viral clearance after peginterferon and ribavirin therapy. S-adenosyl methionine (SAMe) increases interferon signaling in cell culture. We assessed the effect of SAMe on the kinetics of the ear...

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Hlavní autoři: Feld, Jordan J., Modi, Apurva A., El-Diwany, Ramy, Rotman, Yaron, Thomas, Emmanuel, Koh, Christopher, Cherepanov, Vera, Heller, Theo, Ghany, Marc G., Park, Yoon, Hoofnagle, Jay H., Liang, T. Jake
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021477/
https://ncbi.nlm.nih.gov/pubmed/20854821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.09.010
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