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Early Changes in Interferon Signaling Define Natural Killer Cell Response and Refractoriness To Interferon-based Therapy of Hepatitis C
Natural killer (NK) cells exhibit a polarized phenotype with increased cytotoxicity and decreased IFN- γ production in chronic hepatitis C virus (HCV) infection. Here we asked whether this is due to type I interferon (IFN)-induced expression and phosphorylation levels of signal transducer and activa...
Bewaard in:
Hoofdauteurs: | , , , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2011
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3353526/ https://ncbi.nlm.nih.gov/pubmed/21898483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24628 |
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