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Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA Signaling
The major cAMP receptors in eukaryotes are the regulatory (R) subunits of PKA, an allosteric enzyme conserved in fungi through mammals. While mammals have four R-subunit genes, Saccharomyces cerevisiae has only one, Bcy1. To achieve a molecular understanding of PKA activation in yeast and to explore...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3435106/ https://ncbi.nlm.nih.gov/pubmed/21070946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.08.013 |
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