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Evaluation of the toxicity of 2-aminoimidazole antibiofilm agents using both cellular and model organism systems

Biofilm formation is a ubiquitous bacterial defense mechanism and has been shown to be a primary element in the antibiotic resistance of many human diseases, especially in the case of nosocomial infections. Recently, we have developed several compound libraries that are extremely effective at both d...

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Autors principals: Stowe, Sean D., Tucker, Ashley T., Thompson, Richele, Piper, Amanda, Richards, Justin J., Rogers, Steven A., Mathies, Laura D., Melander, Christian, Cavanagh, John
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434693/
https://ncbi.nlm.nih.gov/pubmed/22292413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01480545.2011.614620
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