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Amide Isosteres of Oroidin: Assessment of Antibiofilm Activity and C. elegans Toxicity
The synthesis and antibiofilm activities of sulfonamide, urea, and thiourea oroidin analogues are described. The most active derivative was able to selectively inhibit P. aeruginosa biofilm development and is also shown to be non-toxic upwards of 1 mM to the development of C. elegans in comparison t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739084/ https://ncbi.nlm.nih.gov/pubmed/19719234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900378s |
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