Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2-aminoimidazole-based compounds

With antibiotic resistance increasing at alarming rates, targets for new antimicrobial therapies must be identified. A particularly promising target is the bacterial two-component system. Two-component systems allow bacteria to detect, evaluate and protect themselves against changes in the environme...

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Publicado no:Mol Microbiol
Main Authors: Milton, Morgan E., Allen, C. Leigh, Feldmann, Erik A., Bobay, Benjamin G., Jung, David K., Stephens, Matthew D., Melander, Roberta J., Theisen, Kelly E., Zeng, Daina, Thompson, Richele J., Melander, Christian, Cavanagh, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630518/
https://ncbi.nlm.nih.gov/pubmed/28755524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13759
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