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Aspartoacylase supports oxidative energy metabolism during myelination
The inherited leukodystrophy Canavan disease arises due to a loss of the ability to catabolize N-acetylaspartic acid (NAA) in the brain and constitutes a major point of focus for efforts to define NAA function. Accumulation of noncatabolized NAA is diagnostic for Canavan disease, but contrasts with...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434629/ https://ncbi.nlm.nih.gov/pubmed/22617649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.66 |
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