Blocking of bradykinin receptor B1 protects from focal closed head injury in mice by reducing axonal damage and astroglia activation

The two bradykinin receptors B1R and B2R are central components of the kallikrein–kinin system with different expression kinetics and binding characteristics. Activation of these receptors by kinins triggers inflammatory responses in the target organ and in most situations enhances tissue damage. We...

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Hlavní autoři: Albert-Weissenberger, Christiane, Stetter, Christian, Meuth, Sven G, Göbel, Kerstin, Bader, Michael, Sirén, Anna-Leena, Kleinschnitz, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434625/
https://ncbi.nlm.nih.gov/pubmed/22569191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.62
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