Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa

BACKGROUND: Traumatic brain injury (TBI) is a devastating neurological condition and a frequent cause of permanent disability. Posttraumatic inflammation and brain edema formation, two pathological key events contributing to secondary brain injury, are mediated by the contact-kinin system. Activatio...

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Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Hopp, Sarah, Nolte, Marc W., Stetter, Christian, Kleinschnitz, Christoph, Sirén, Anna-Leena, Albert-Weissenberger, Christiane
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319055/
https://ncbi.nlm.nih.gov/pubmed/28219400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0815-8
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