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Mus81-Mms4 Functions as a Single Heterodimer To Cleave Nicked Intermediates in Recombinational DNA Repair

The formation of crossovers is a fundamental genetic process. The XPF-family endonuclease Mus81-Mms4 (Eme1) contributes significantly to crossing over in eukaryotes. A key question is whether Mus81-Mms4 can process Holliday junctions that contain four uninterrupted strands. Holliday junction cleavag...

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Detalhes bibliográficos
Main Authors: Schwartz, Erin K., Wright, William D., Ehmsen, Kirk T., Evans, James E., Stahlberg, Henning, Heyer, Wolf-Dietrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434506/
https://ncbi.nlm.nih.gov/pubmed/22645308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00547-12
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