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BNip3 Regulates Mitochondrial Function and Lipid Metabolism in the Liver

BNip3 localizes to the outer mitochondrial membrane, where it functions in mitophagy and mitochondrial dynamics. While the BNip3 protein is constitutively expressed in adult liver from fed mice, we have shown that its expression is superinduced by fasting of mice, consistent with a role in responses...

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Detalhes bibliográficos
Main Authors: Glick, Danielle, Zhang, Wenshuo, Beaton, Michelle, Marsboom, Glenn, Gruber, Michaela, Simon, M. Celeste, Hart, John, Dorn, Gerald W., Brady, Matthew J., Macleod, Kay F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434502/
https://ncbi.nlm.nih.gov/pubmed/22547685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00167-12
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