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Krüppel-Like Factor 1 (KLF1), KLF2, and Myc Control a Regulatory Network Essential for Embryonic Erythropoiesis
The Krüppel-like factor 1 (KLF1) and KLF2 positively regulate embryonic β-globin expression and have additional overlapping roles in embryonic (primitive) erythropoiesis. KLF1(−/−) KLF2(−/−) double knockout mice are anemic at embryonic day 10.5 (E10.5) and die by E11.5, in contrast to single knockou...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434496/ https://ncbi.nlm.nih.gov/pubmed/22566683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00104-12 |
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