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Gbx2 Directly Restricts Otx2 Expression to Forebrain and Midbrain, Competing with Class III POU Factors

Otx2 plays essential roles in rostral brain development, and its counteraction with Gbx2 has been suggested to determine the midbrain-hindbrain boundary (MHB) in vertebrates. We previously identified the FM enhancer that is conserved among vertebrates and drives Otx2 transcription in forebrain/midbr...

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Bibliografische gegevens
Hoofdauteurs: Inoue, Fumitaka, Kurokawa, Daisuke, Takahashi, Maiko, Aizawa, Shinichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434480/
https://ncbi.nlm.nih.gov/pubmed/22566684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00083-12
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