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Gbx2 Directly Restricts Otx2 Expression to Forebrain and Midbrain, Competing with Class III POU Factors

Otx2 plays essential roles in rostral brain development, and its counteraction with Gbx2 has been suggested to determine the midbrain-hindbrain boundary (MHB) in vertebrates. We previously identified the FM enhancer that is conserved among vertebrates and drives Otx2 transcription in forebrain/midbr...

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Detalhes bibliográficos
Main Authors: Inoue, Fumitaka, Kurokawa, Daisuke, Takahashi, Maiko, Aizawa, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434480/
https://ncbi.nlm.nih.gov/pubmed/22566684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00083-12
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