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Acetylated YY1 regulates Otx2 expression in anterior neuroectoderm at two cis-sites 90 kb apart

The mouse homeobox gene Otx2 plays essential roles at each step and in every tissue during head development. We have previously identified a series of enhancers that are responsible for driving the Otx2 expression in these contexts. Among them the AN enhancer, existing 92 kb 5′ upstream, directs Otx...

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Détails bibliographiques
Auteurs principaux: Takasaki, Nobuyoshi, Kurokawa, Daisuke, Nakayama, Rika, Nakayama, Jun-ichi, Aizawa, Shinichi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829384/
https://ncbi.nlm.nih.gov/pubmed/17332747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601619
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