Identification of binding pockets in protein structures using a knowledge-based potential derived from local structural similarities

BACKGROUND: The identification of ligand binding sites is a key task in the annotation of proteins with known structure but uncharacterized function. Here we describe a knowledge-based method exploiting the observation that unrelated binding sites share small structural motifs that bind the same che...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bianchi, Valerio, Gherardini, Pier Federico, Helmer-Citterich, Manuela, Ausiello, Gabriele
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434446/
https://ncbi.nlm.nih.gov/pubmed/22536963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S4-S17
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky