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Functional annotation by identification of local surface similarities: a novel tool for structural genomics

BACKGROUND: Protein function is often dependent on subsets of solvent-exposed residues that may exist in a similar three-dimensional configuration in non homologous proteins thus having different order and/or spacing in the sequence. Hence, functional annotation by means of sequence or fold similari...

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Detalhes bibliográficos
Main Authors: Ferrè, Fabrizio, Ausiello, Gabriele, Zanzoni, Andreas, Helmer-Citterich, Manuela
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190158/
https://ncbi.nlm.nih.gov/pubmed/16076399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-6-194
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