β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial–mesenchymal transition

Human lung cancers, including squamous cell carcinoma (SCC) are a leading cause of death and, whilst evidence suggests that basal stem cells drive SCC initiation and progression, the mechanisms regulating these processes remain unknown. In this study we show that β-catenin signalling regulates basal...

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Autori principali: Giangreco, Adam, Lu, Liwen, Vickers, Charles, Teixeira, Vitor Hugo, Groot, Karen R, Butler, Colin R, Ilieva, Ekaterina V, George, P Jeremy, Nicholson, Andrew G, Sage, Elizabeth K, Watt, Fiona M, Janes, Sam M
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd. 2012
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Original Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434372/
https://ncbi.nlm.nih.gov/pubmed/22081448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.3962
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