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Dissecting DNA damage response pathways by analyzing protein localization and abundance changes during DNA replication stress
Re-localization of proteins is a hallmark of the DNA damage response. We use high-throughput microscopic screening of the yeast GFP fusion collection to develop a systems-level view of protein re-organization following drug-induced DNA replication stress. Changes in protein localization and abundanc...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434236/ https://ncbi.nlm.nih.gov/pubmed/22842922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2549 |
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