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Leveraging DNA Damage Response Signaling to Identify Yeast Genes Controlling Genome Stability

Oncogenesis frequently is accompanied by rampant genome instability, which fuels genetic heterogeneity and resistance to targeted cancer therapy. We have developed an approach that allows precise, quantitative measurement of genome instability in high-throughput format in the Saccharomyces cerevisia...

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書目詳細資料
發表在:G3 (Bethesda)
Main Authors: Hendry, Jason A., Tan, Guihong, Ou, Jiongwen, Boone, Charles, Brown, Grant W.
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426383/
https://ncbi.nlm.nih.gov/pubmed/25721128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.016576
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