A Conserved Domain of Schizosaccharomyces pombe dfp1(+) Is Uniquely Required for Chromosome Stability following Alkylation Damage during S Phase

The fission yeast Dbf4 homologue Dfp1 has a well-characterized role in regulating the initiation of DNA replication. Sequence analysis of Dfp1 homologues reveals three highly conserved regions, referred to as motifs N, M, and C. To determine the roles of these conserved regions in Dfp1 function, we...

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Detalhes bibliográficos
Main Authors: Fung, Amy D., Ou, Jiongwen, Bueler, Stephanie, Brown, Grant W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133926/
https://ncbi.nlm.nih.gov/pubmed/12052858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4477-4490.2002
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