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Probing the activation sequence of NMDA receptors with lurcher mutations
N-methyl-d-aspartate (NMDA) receptor activation involves a dynamic series of structural rearrangements initiated by glutamate binding to glycine-loaded receptors and culminates with the clearing of the permeation pathway, which allows ionic flux. Along this sequence, three rate-limiting transitions...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434102/ https://ncbi.nlm.nih.gov/pubmed/22891278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210786 |
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