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Probing the Structural Dynamics of the NMDA Receptor Activation by Coarse-Grained Modeling

N-Methyl-D-aspartate (NMDA) receptors are glutamate-gated excitatory channels that play essential roles in brain functions. High-resolution structures have been solved for an allosterically inhibited and agonist-bound form of a functional NMDA receptor; however, other key functional states (particul...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Zheng, Wenjun, Wen, Han, Iacobucci, Gary J., Popescu, Gabriela K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479051/
https://ncbi.nlm.nih.gov/pubmed/28636915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.04.043
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