Zinc Effects on NMDA Receptor Gating Kinetics

Zinc accumulates in the synaptic vesicles of certain glutamatergic forebrain neurons and modulates neuronal excitability and synaptic plasticity by multiple poorly understood mechanisms. Zinc directly inhibits NMDA-sensitive glutamate-gated channels by two separate mechanisms: high-affinity binding...

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Main Authors: Amico-Ruvio, Stacy A., Murthy, Swetha E., Smith, Thomas P., Popescu, Gabriela K.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2011
Assuntos:
Channels and Transporters
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077707/
https://ncbi.nlm.nih.gov/pubmed/21504727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.02.042
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