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Modeling suggests that gene circuit architecture controls phenotypic variability in a bacterial persistence network

BACKGROUND: Bacterial persistence is a non-inherited bet-hedging mechanism where a subpopulation of cells enters a dormant state, allowing those cells to survive environmental stress such as treatment with antibiotics. Persister cells are not mutants; they are formed by natural stochastic variation...

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Autori principali: Koh, Rachel S, Dunlop, Mary J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434061/
https://ncbi.nlm.nih.gov/pubmed/22607777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-47
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