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Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence
In the face of antibiotics, bacterial populations avoid extinction by harboring a subpopulation of dormant cells that are largely drug insensitive. This phenomenon, termed “persistence,” is a major obstacle for the treatment of a number of infectious diseases. The mechanism that generates both activ...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906590/ https://ncbi.nlm.nih.gov/pubmed/20616060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004333107 |
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