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Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence

In the face of antibiotics, bacterial populations avoid extinction by harboring a subpopulation of dormant cells that are largely drug insensitive. This phenomenon, termed “persistence,” is a major obstacle for the treatment of a number of infectious diseases. The mechanism that generates both activ...

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Detaylı Bibliyografya
Asıl Yazarlar: Rotem, Eitan, Loinger, Adiel, Ronin, Irine, Levin-Reisman, Irit, Gabay, Chana, Shoresh, Noam, Biham, Ofer, Balaban, Nathalie Q.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906590/
https://ncbi.nlm.nih.gov/pubmed/20616060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004333107
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