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An autoregulatory loop reverts the mechanosensitive Sirt1 induction by EGR1 in skeletal muscle cells

Muscle contraction is associated with the production of reactive oxygen species (ROS). Mechanisms of ROS scavenging are fundamental to avoid muscle damage. We had previously discovered a stretch-induced genetic program in myotubes that triggers an antioxidant defense. At the core of this mechanism,...

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Sonraí Bibleagrafaíochta
Main Authors: Pardo, Patricia S., Boriek, Aladin M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433932/
https://ncbi.nlm.nih.gov/pubmed/22820707
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