SIRT1 Controls the Transcription of the Peroxisome Proliferator-activated Receptor-γ Co-activator-1α (PGC-1α) Gene in Skeletal Muscle through the PGC-1α Autoregulatory Loop and Interaction with MyoD

Peroxisome proliferator activated receptor-γ co-activator-1α (PGC-1α) is a transcriptional co-activator that coordinately regulates the expression of distinct sets of metabolism-related genes in different tissues. Here we show that PGC-1α expression is reduced in skeletal muscles from mice lacking t...

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Bibliographic Details
Main Authors: Amat, Ramon, Planavila, Anna, Chen, Shen Liang, Iglesias, Roser, Giralt, Marta, Villarroya, Francesc
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Molecular Basis of Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755911/
https://ncbi.nlm.nih.gov/pubmed/19553684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.022749
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