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SIRT1 Controls the Transcription of the Peroxisome Proliferator-activated Receptor-γ Co-activator-1α (PGC-1α) Gene in Skeletal Muscle through the PGC-1α Autoregulatory Loop and Interaction with MyoD
Peroxisome proliferator activated receptor-γ co-activator-1α (PGC-1α) is a transcriptional co-activator that coordinately regulates the expression of distinct sets of metabolism-related genes in different tissues. Here we show that PGC-1α expression is reduced in skeletal muscles from mice lacking t...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755911/ https://ncbi.nlm.nih.gov/pubmed/19553684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.022749 |
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