Induction of Sirt1 by Mechanical Stretch of Skeletal Muscle through the Early Response Factor EGR1 Triggers an Antioxidative Response

Mechanical loading of muscles by intrinsic muscle activity or passive stretch leads to an increase in the production of reactive oxygen species (1, 2). The NAD-dependent protein deacetylase SIRT1 is involved in the protection against oxidative stress by enhancing FOXO-driven Sod2 transcription (3–5)...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Pardo, Patricia S., Mohamed, Junaith S., Lopez, Michael A., Boriek, Aladin M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024751/
https://ncbi.nlm.nih.gov/pubmed/20971845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149153
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker