Haploinsufficiency of Tumor Suppressor Genes is Driven by the Cumulative Effect of microRNAs, microRNA Binding Site Polymorphisms and microRNA Polymorphisms: An In silico Approach

Haploinsufficiency of tumor suppressor genes, wherein the reduced production and activity of proteins results in the inability of the cell to maintain normal cellular function, is one among the various causes of cancer. However the precise molecular mechanisms underlying this condition remain unclea...

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Autores principales: Manikandan, Mayakannan, Raksha, Ganesh, Munirajan, Arasambattu Kannan
Formato: Artigo
Lenguaje:Inglês
Publicado: Libertas Academica 2012
Materias:
Perspective
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433856/
https://ncbi.nlm.nih.gov/pubmed/23032637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CIN.S10176
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