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Haploinsufficiency of Tumor Suppressor Genes is Driven by the Cumulative Effect of microRNAs, microRNA Binding Site Polymorphisms and microRNA Polymorphisms: An In silico Approach
Haploinsufficiency of tumor suppressor genes, wherein the reduced production and activity of proteins results in the inability of the cell to maintain normal cellular function, is one among the various causes of cancer. However the precise molecular mechanisms underlying this condition remain unclea...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Libertas Academica
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433856/ https://ncbi.nlm.nih.gov/pubmed/23032637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CIN.S10176 |
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