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Single Nucleotide Polymorphisms in MicroRNA Binding Sites of Oncogenes: Implications in Cancer and Pharmacogenomics

Cancer, a complex genetic disease involving uncontrolled cell proliferation, is caused by inactivation of tumor suppressor genes and activation of oncogenes. A vast majority of these cancer causing genes are known targets of microRNAs (miRNAs) that bind to complementary sequences in 3′ untranslated...

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Detalles Bibliográficos
Main Authors: Manikandan, Mayakannan, Munirajan, Arasambattu Kannan
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920756/
https://ncbi.nlm.nih.gov/pubmed/24286505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2013.0098
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