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The molecular basis for high affinity of a universal ligand for human bombesin receptor (BnR) family members
There is increased interest in the Bn-receptor family because they are frequently over/ectopically-expressed by tumors and thus useful as targets for imaging or receptor-targeted-cytotoxicity. The synthetic Bn-analog,[D-Tyr(6),β-Ala(11),Phe(13),Nle(14)]Bn(6-14)[Univ.Lig] has the unique property of h...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433740/ https://ncbi.nlm.nih.gov/pubmed/22828605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.07.010 |
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