The combination of RAD001 and NVP-BKM120 synergistically inhibits the growth of lung cancer in vitro and in vivo

This study focuses on determining whether the combination of NYP-BKM120 (BKM120) and RAD001 exerts enhanced therapeutic effect against lung cancer. The combination of BKM120 and RAD001 exerted synergistic inhibitory effects on the growth of lung cancer cells both in culture and in mouse xenograft mo...

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Bibliografiske detaljer
Main Authors: Ren, Hui, Chen, Mingwei, Yue, Ping, Tao, Hui, Owonikoko, Taofeek K., Ramalingam, Suresh S., Khuri, Fadlo R., Sun, Shi-Yong
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433638/
https://ncbi.nlm.nih.gov/pubmed/22781393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.06.018
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