Augmentation of NVP-BEZ235's anticancer activity against human lung cancer cells by blockage of autophagy

Autophagy is a cellular lysosomal degradation pathway essential for regulation of cell survival and death to maintain homeostasis. This process is negatively regulated by mammalian target of rapamycin (mTOR) signaling and often counteracts efficacy of certain cancer therapeutic agents. NVP-BEZ235 (B...

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Detalhes bibliográficos
Main Authors: Xu, Cheng-Xiong, Zhao, Liqun, Yue, Ping, Fang, Guofu, Tao, Hui, Owonikoko, Taofeek K, Ramalingam, Suresh S, Khuri, Fadlo R, Sun, Shi-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218593/
https://ncbi.nlm.nih.gov/pubmed/21738008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.12.6.16397
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