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Augmentation of NVP-BEZ235's anticancer activity against human lung cancer cells by blockage of autophagy

Autophagy is a cellular lysosomal degradation pathway essential for regulation of cell survival and death to maintain homeostasis. This process is negatively regulated by mammalian target of rapamycin (mTOR) signaling and often counteracts efficacy of certain cancer therapeutic agents. NVP-BEZ235 (B...

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Detaylı Bibliyografya
Asıl Yazarlar: Xu, Cheng-Xiong, Zhao, Liqun, Yue, Ping, Fang, Guofu, Tao, Hui, Owonikoko, Taofeek K, Ramalingam, Suresh S, Khuri, Fadlo R, Sun, Shi-Yong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218593/
https://ncbi.nlm.nih.gov/pubmed/21738008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.12.6.16397
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