Augmentation of NVP-BEZ235's anticancer activity against human lung cancer cells by blockage of autophagy

Autophagy is a cellular lysosomal degradation pathway essential for regulation of cell survival and death to maintain homeostasis. This process is negatively regulated by mammalian target of rapamycin (mTOR) signaling and often counteracts efficacy of certain cancer therapeutic agents. NVP-BEZ235 (B...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Xu, Cheng-Xiong, Zhao, Liqun, Yue, Ping, Fang, Guofu, Tao, Hui, Owonikoko, Taofeek K, Ramalingam, Suresh S, Khuri, Fadlo R, Sun, Shi-Yong
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2011
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218593/
https://ncbi.nlm.nih.gov/pubmed/21738008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.12.6.16397
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