Plasmin Triggers a Switch-Like Decrease in Thrombospondin-Dependent Activation of TGF-β1

Transforming growth factor-β1 (TGF-β1) is a potent regulator of extracellular matrix production, wound healing, differentiation, and immune response, and is implicated in the progression of fibrotic diseases and cancer. Extracellular activation of TGF-β1 from its latent form provides spatiotemporal...

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Main Authors: Venkatraman, Lakshmi, Chia, Ser-Mien, Narmada, Balakrishnan Chakrapani, White, Jacob K., Bhowmick, Sourav S., Forbes Dewey, C., So, Peter T., Tucker-Kellogg, Lisa, Yu, Hanry
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2012
Assuntos:
Systems Biophysics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433618/
https://ncbi.nlm.nih.gov/pubmed/23009856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.050
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