Steady States and Dynamics of Urokinase-Mediated Plasmin Activation In Silico and In Vitro

Plasmin (PLS) and urokinase-type plasminogen activator (UPA) are ubiquitous proteases that regulate the extracellular environment. Although they are secreted in inactive forms, they can activate each other through proteolytic cleavage. This mutual interplay creates the potential for complex dynamics...

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Detalhes bibliográficos
Main Authors: Venkatraman, Lakshmi, Li, Huipeng, Dewey, C. Forbes, White, Jacob K., Bhowmick, Sourav S., Yu, Hanry, Tucker-Kellogg, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Biological Systems and Multicellular Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192967/
https://ncbi.nlm.nih.gov/pubmed/22004735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.054
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