HuR contributes to Hepatic Stellate Cell activation and liver fibrosis

RNA-binding proteins (RBPs) play a major role in control of mRNA turnover and translation rates. We examined the role of the RBP human antigen R (HuR) during cholestatic liver injury and hepatic stellate cells (HSC) activation. HuR silencing attenuated fibrosis development in vivo after BDL, reducin...

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Main Authors: Woodhoo, A., Iruarrizaga-Lejarreta, M., Beraza, N., García-Rodríguez, J.L., Embade, N., Fernández-Ramos, D., Matinez-Lopez, N., Gutiérrez, Virginia, Arteta, B., Caballeria, J., Lu, S.C., Mato, J.M., Varela-Rey, M., Martinez-Chantar, M.L.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433583/
https://ncbi.nlm.nih.gov/pubmed/22576182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25828
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