HuR/Methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation and carcinogenesis

BACKGROUND & AIMS: Hepatic de-differentiation, liver development, and malignant transformation are processes in which the levels of hepatic S-adenosylmethionine (SAMe) are tightly regulated by two genes, MAT1A and MAT2A. MAT1A is expressed in the adult liver, whereas MAT2A expression is primaril...

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Main Authors: Vázquez-Chantada, Mercedes, Fernández-Ramos, David, Embade, Nieves, Martínez-Lopez, Nuria, Varela-Rey, Marta, Woodhoo, Ashwin, Luka, Zigmund, Wagner, Conrad, Anglim, Paul P., Finnell, Richard H., Caballería, Juan, Laird-Offringa, Ite A., Gorospe, Myriam, Lu, Shelly C, Mato, José M, Martínez-Chantar, M Luz
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860011/
https://ncbi.nlm.nih.gov/pubmed/20102719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.01.032
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