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Transient decrease in nociceptor GRK2 expression produces long–term enhancement in inflammatory pain
In heterozygous mice, attenuation of G-protein-coupled receptor kinase 2 (GRK2) level in nociceptors is associated with enhanced and prolonged inflammatory hyperalgesia. To further elucidate the role of GRK2 in nociceptor function we reversibly decreased GRK2 expression using intrathecal antisense o...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433493/ https://ncbi.nlm.nih.gov/pubmed/22796071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.07.004 |
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