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Generation of a Pain Memory in the Primary Afferent Nociceptor Triggered by PKCε Activation of CPEB
Isolectin B(4)-positive [IB(4)(+)] primary afferent nociceptors challenged with an inflammatory or neuropathic insult develop a PKCε-dependent long-lasting hyperalgesic response to a subsequent challenge by the proinflammatory cytokine prostaglandin E(2) (PGE(2)), a phenomenon known as hyperalgesic...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3305286/ https://ncbi.nlm.nih.gov/pubmed/22323716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5138-11.2012 |
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